This is a limited tenure position with an anticipated end date of June 1, 2027

The Senior Manager of IT Infrastructure will be responsible for the design, implementation and operational leadership of infrastructure services supporting a laboratory. This role plays a key part in building IT capabilities in a new company, operating independently while remaining aligned with Mayo governance, security, and quality standards during the build and early operational phases.

Reporting to the IT Director, the Senior Manager has primary accountability for infrastructure services delivered through managed service provider relationships, including network, hosting, cloud platforms, end-user computing, and foundational security services. The role ensures infrastructure reliability, performance, scalability, and compliance required to support laboratory operations, business continuity, and future growth.

Working closely with the IT Director, laboratory leadership, cybersecurity, and Mayo Collaborative Services technology partners, the Senior Manager will help establish and mature infrastructure operating practices, including monitoring, incident response, change management, disaster recovery, and capacity planning. The role requires strong operational leadership, vendor management expertise, and experience supporting highly available, mission-critical systems in regulated environments.

This position is a limited-tenure role intended to support the formation, launch, and stabilization of the new company and laboratory. As the organization matures, the role is expected to transition to a permanent infrastructure leadership position within a separate company operating independently from Mayo Collaborative Services.

The ideal candidate will have experience leading infrastructure services in laboratory, healthcare, life sciences, or similarly regulated environments, with the ability to operate independently while remaining aligned with a broader enterprise governance, security, and compliance framework.

This position is not eligible for sponsorship/we will not sponsor or transfer a visa for this position. Also, Mayo Clinic DOES NOT participate in the F1-STEM OPT extension program.

Bachelor’s degree in Information Technology, Business, Design, Healthcare Administration, or a related field. Minimum of 8 years of progressive leadership experience in digital product, technology operations, service delivery, or equivalent roles. Demonstrated experience managing teams, influencing strategy, and implementing complex organizational initiatives.

Master’s degree in Business Administration, Public Health, Information Systems, or related discipline preferred.

Requires frequent travel including to national lab facilities and Mayo Collaborative Services headquarters in Rochester, MN.