Principal Developer - Next Generation Sequencing - Translational Research, Innovation & Test Development Office (TRITDO)
Job ID 391445 Date posted 09/16/2026- Rochester, Minnesota
- Full Time
- Laboratory Medicine & Pathology
- Remote: No
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
Division/Departmental test development/innovation platform leader who develops, innovates, evaluates, and implements novel/new tests, methodologies, technologies, or products for the laboratory under the intellectual and scientific guidance of laboratory directors and senior principal developer. Test development/innovation platform leader responsible for development/innovation support of multiple projects across the division/department. Responsible for improvement of existing methods or implementation of novel technology of proven validity. Test development/innovation platform leader on cross-departmental teams, including Bioinformatics and IT, to create final recommendations to the laboratory directors and supervisors in the evaluation of novel laboratory equipment, instrumentation, procedures, and computer software and hardware. Test development/innovation platform leader and mentor for test development /innovation staff.
**This position is not eligible for visa sponsorship. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program**
We require a two year commitment to this role
Qualifications
Bachelor's degree in clinical/medical laboratory science (CLS/MLS), medical technology (MT), chemistry, biological science from an accredited institution or bachelor’s degree from an accredited institution in addition to a certificate in MLS. Six years of relevant laboratory experience; or a Master's degree from an accredited institution in chemical, physical, biological, clinical laboratory science or medical technology and four years of relevant laboratory experience; or a Doctoral degree in chemistry or a biological science and two years of relevant laboratory experience. A HEW certificate may be substituted for the specified degree. Other clinical laboratory specialty certificates will be reviewed and approved on a case-by-case basis. Master's degree or Doctoral (PhD) degree from an accredited institution in chemical, physical, biological, clinical laboratory science or medical technology preferred. Test development/innovation leader for multiple complex cross-area projects.
Additional Qualifications
- Demonstrated ability to work independently with a high degree of initiative, organization, and efficiency while exercising sound judgment, decision-making, and project management skills.
- Excellent written and verbal communication skills, with the ability to effectively collaborate across multidisciplinary teams.
- Proven ability to interpret and apply scientific literature, reference materials, and existing methodologies to develop and implement innovative laboratory methods, processes, or products.
- Adaptable and flexible in managing multiple projects involving diverse technologies, platforms, and scientific disciplines.
- Strong analytical, problem-solving, and scientific expertise with comprehensive knowledge of laboratory procedures and best practices.
- Extensive experience with Next Generation Sequencing (NGS) technologies, including assay development, optimization, validation, and data interpretation.
License or Certification:
ASCP or other certification pertinent to the laboratory field may be required depending on the laboratory specialty and prevailing regulatory requirements. Employees obtaining CT certification(s) after January 1, 2004 will be required to demonstrate evidence of ongoing maintenance of certification. Employees obtaining SCT certification(s) after January 1, 2006 will be required to demonstrate evidence of ongoing maintenance of certification.
Exemption Status
Exempt
Compensation Detail
$85,467 - $128,252/ year
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Typically, Monday-Friday day shift with some flexibility for hours. Potential for some intermittent remote work as projects allow.
Weekend Schedule
No regularly scheduled weekends but could possibly be required based on specific project needs.
International Assignment
No
Site Description
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
Rhonda Wilson
Join our talent community.
From roles that are right for you to new opportunities, keep up-to-date on job openings and more.
Jobs for you
- Mankato, Minnesota Environmental Services Technician Housekeeping
- Jacksonville, Florida Registered Nurse - Emergency Department, Swing - RN Nursing RN
- Eau Claire, Wisconsin Nurse Practitioner or Physician Assistant - Inpatient Cardiology (Nights) Cardiology, Nurse Practitioner, Physician Assistant
- Jacksonville, Florida Registered Nurse - Emergency Department, Nights - RN Nursing RN
You have no Recently Viewed Jobs. View all available opportunities.
-
About Us
If you want to know what it's really like at Mayo Clinic, just ask. You'll find that our pride–in where we work, and in what we do–is a common trait. You will also find a lot of inspiring stories about lives changed for the better.
-
Nurse Residency Program
The Nurse Residency Program (NRP) is for all nurses with less than 12 months of experience, to be completed within the first year. NRP provides a framework for a successful transtion to a professional nurse by promoting educational and personal advancement.
-
Benefits
As your career evolves, our compensation and benefits packages are designed to change with you — meeting needs now, and anticipating what comes next. We know that when Mayo Clinic takes care of you, you can take better care of our patients.
Equal opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status, or disability status. Learn more about "EEO is the Law." Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Wage and Hour Divisions FMLA poster
Employee Polygraph Protection Act Rights Poster
Mayo Equal Employment Opportunity Policy 2025
Reasonable accommodations
Mayo Clinic provides reasonable accommodations to individuals with disabilities to support equal access and remove barriers to employment. If you need a reasonable accommodation during the recruitment process—including accessing job postings, completing an application, participating in an interview, completing pre-employment testing, or during onboarding—please contact HR Connect at 507-266-0440 or 888-266-0440.
Job offers
Job offers are contingent upon successful completion of a post offer placement assessment including a urine drug screen, immunization review and tuberculin (TB) skin testing, if applicable.
Recruitment Fraud
Learn more about recruitment fraud and job scams
Advertising
Mayo Clinic is a not-for-profit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not endorse any of the third party products and services advertised.
Advertising and sponsorship policy | Advertising and sponsorship opportunities
Reprint permissions
A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.
Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.
Manage Cookies | Terms and Conditions | Privacy Policy | Notice of Privacy Practices | Notice of Nondiscrimination
© 1998-2026 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.