We are seeking a driven postdoctoral research fellow with molecular biology and computational research experience to join our collaborative research team. 

Dr. Conboy’s hepatobiliary oncology lab is focused on understanding molecular mechanisms of cancer to improve cancer therapies. Current projects seek to define underlying mechanisms and functional consequences of epigenetic dysregulation in cholangiocarcinoma, using novel mouse models, syngenic cell lines, and patient-derived models. We are interrogating models and patient datasets to (1) understand pathogenesis and (2) develop targeted treatment approaches. The long-term goal of this work is to identify promising strategies to bring to clinical trials to improve outcomes for patients with cholangiocarcinoma.

The research environment is enriched by a multidisciplinary working group including collaborators in the Division of Medical Oncology, Gastroenterology and Hepatology, Hepatobiliary Surgery, and Pharmacology. We collaborate closely with the NIH-funded Hepatobiliary Specialized Program of Research Excellence (SPORE), the NIH P30-funded Center for Cell Signaling in Gastroenterology (C-SiG) and the Mayo Clinic Comprehensive Cancer Center. This is a scientific environment with a strong commitment to basic and translational research in liver diseases.

Successful candidates will be motivated and rigorous PhD scientists with experience in molecular and/or computational biology. Ideal candidates should have experience with molecular and cell biology techniques including DNA/RNA/protein assays, cell culture and cell-based assays. Prior experience or interest in mouse work is optional. Computational skillsets including programming in R or python, facility with analysis and visualization of large “omics” datasets, and statistical hypothesis testing are highly desired. 

Must have a Ph.D., M.D., or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship, at Mayo Clinic or elsewhere.