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Senior AI/ML Program Manager - Digital Portfolio

Job ID 390858 Date posted 09/08/2026 Job Expiration Date 09/11/2026
  • Rochester, MN
  • Full Time
  • Remote: No
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Overview

Be challenged to deliver innovative solutions that will change health care.

Mayo Clinic’s tech culture is rooted in passion for technology, embraces innovative thinking and strives for high performance. Our teams drive change in health care through comprehensive connected health and digital transformation strategies.

Some examples of our major initiatives are:

  • Utilizing artificial intelligence and machine learning principles to develop next generation patient centric care systems
  • Transforming the practice by applying data science techniques to discover new approaches to health care delivery
  • Leveraging Enterprise Architecture to construct integration centricity, promote data liquidity, and provide innovation support

This transformation creates, connects and applies integrated knowledge to deliver the best health care, health guidance and health information to patients, customers, partners, providers, employees anywhere and anytime so the needs of the patient come first.

Job Description

CityRochester

StateMN

RemoteNO

DepartmentInformation Technology

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.


Responsibilities

Mayo Clinic’s Senior Program Manager- Digital Technology will work in the Department of AI Implementation and Adoption with the purpose of extending our expertise through digital, data and AI enablement to consumers, patients, and providers to improve their health journey. The senior program manager will provide expertise for complex programs to ensure they can execute Mayo Clinic’s digital roadmap. The Senior Program Manager will lead the team in establishing program direction, identifying interdependencies, communicating program requirements, tracking progress, making decisions, and resolving conflicts and issues for complex program assignments.

Responsibilities:
•   Responsible for guiding the Agile product team in planning and developing scope, deliverables, required resources, work plan and timing for complex initiatives.
•   Coordinates work of multiple products/teams through integrated quarterly planning and backlog/roadmap development.
•   Understands product strategy, and objectives and ensures organizational alignment to organizational strategy. 
•   Achieves visibility and transparency across product teams.
•   Manages program/initiative risks and interdependencies, including mitigation strategies and contingency plans.
•   Accountable for delivering against established business goals/objectives.
•   Leverages data and metrics to communicate status reporting, and monitor ongoing program progress and performance.
•   Ensures operational feasibility and readiness for products.
•   Uses innovative thinking and advanced facilitation skills to build relationships across the organization. Characterized by the ability to work with people from diverse backgrounds
•   Overall program responsibility for a set of interrelated projects of very large size and/or high complexity, under the direction of senior level leadership.
•   Leads a high-performing cross-functional team that collaborates effectively and efficiently with business partners, customers, and other stakeholders.
•   Communicates complex technical information in unambiguous terms to management and end users.
•   Mentors members of the team.
•   Supports strategic program planning, including roadmap development and execution of multi-year initiatives that may involve multiple interrelationships and complexities, requiring the development and execution of complex program plans.
•   Serves as an internal subject matter expert regarding Agile program management practices, methods, and standards.
•   Actively seeks to understand new and emerging technologies, their capabilities and potential applicability to Mayo Clinic needs.
•   Fosters an internal culture of positive teamwork and transparency that drives excellent service, quality, diversity of thought, an engaging work environment, and an overall continuous improvement mindset.

This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.



Qualifications

•   Bachelor’s Degree required. Master’s degree preferred.
•   Experience managing projects and programs involving multiple technical programs involving multiple technological environments which range in complexity and demonstrates increased depth of responsibilities (13+ years)
•   Experience in program management and working knowledge of agile methodologies.
•   Must demonstrate mastery in the application of PMI Process Groups and Knowledge Areas. Possession of an active Program Management Professional (PgMP) certification, or a comparable current certification from a nationally recognized program management governance body with a specialized emphasis in program management is preferred, but not required.
•   Exceptional communication, negotiation, consensus-building, and listening skills. 
•   Demonstrated competencies in strategic and systems thinking, decision making, leading people, change management, influence without authority, and be able to successfully handle and navigate ambiguous situations.
•   Possess a consumer-centric mindset, humanistic and agile approach aimed at delivery of valuable outcomes. 
•   Ability to collaborate effectively and build strong relationships with business and technical stakeholders with different needs and requirements.
•   Experience navigating transformation in highly regulated industries is a plus.
•   Ability to lead through influence and direct multiple complex products in an ambiguous environment.



Exemption Status

Exempt

Compensation Detail

$148,137.60 - $214,760.00/ year. Education, experience and tenure may be considered along with internal equity when job offers are extended.

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

M-F 8am-5pm This is a hybrid position and must be located within 100 miles of a Mayo Clinic campus for occasional on-site expectations based on business needs.

Weekend Schedule

NA

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.


Recruiter

Laura Percival
Apply Now

Career Path

Discover unlimited opportunities. Your IT career may start as a Help Desk Specialist or Work Station Technician, an intern, or entry-level Analyst/Programmer and develop into a mid- or senior-level technical position. You may choose to grow laterally as a technical expert, learning and supporting many different aspects of IT services. Or you may choose to become part of the leadership team.

  • Applications
  • Business Relationship Management
  • Enterprise Infrastructure
  • Enterprise Architecture
  • Information
    Security
  • Management
  • Project Management and Systems Analysis
  • Quality
    Assurance

The Life Changers

  • When you choose an IT career with Mayo Clinic you will have an opportunity to engage with new and innovative solutions which will improve quality of life and patient outcomes. You will partner with brilliant Physicians and Scientists to help drive translational medicine in a fast-paced environment where creativity, energy, and dedication will result in success.”

    Marie Koctecki
    Senior Manager, IT Service Delivery
  • Over the span of my career, I have worked in multiple divisions across IT and have now advanced to a Service Delivery Manager role, managing a Project Management Office (PMO). The opportunities within the department of IT are vast. I have been able to gain my Project Management Professional (PMP) certification as well as my Certified Scrum Master (CSM) certification while at Mayo Clinic.”

    Betty Hutchins
    Manager, IT Service Delivery
  • I appreciate the breadth of career paths within IT and the ability to branch out and diversify my professional expertise while remaining with Mayo Clinic. The diverse backgrounds and depth of expertise of my coworkers is an attribute of Mayo’s unique culture; I enjoy the opportunity to work with so many world-renowned experts and thought leaders across a wide array of professions.”

    Samanthie Epps
    Manager, IT Speciality Systems

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All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status, or disability status. Learn more about "EEO is the Law." Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

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